Pihlajamäki H, Böstman O, Manninen M, Päivärinta U, Törmälä P, Rokkanen P
Department of Orthopaedics and Traumatology, University Central Hospital, Helsinki, Finland.
Clin Orthop Relat Res. 1994 Jan(298):277-85.
An absorbable plug for the internal fixation of fractures and osteotomies, measuring 4.5 mm in diameter and 30 mm in length, was constructed of poly-L-lactide using a self-reinforcing fibers-in-matrix manufacturing technique. To increase the rotational stability and grip of the device, the plug has deployable distal fins. The plug was used in the fixation of a transverse distal femoral osteotomy in 20 rabbits. The consolidation of the osteotomy was investigated histologically, histomorphometrically, and microradiographically in groups of five rabbits observed for three, six, 12, or 24 weeks. Fifteen osteotomies showed bony union. In five rabbits, no bridging trabeculae across the osteotomy had developed, but these rabbits belonged to the groups with the shortest follow-up times of three or six weeks. No mechanical failures of the plugs were encountered, and the short-term biocompatibility of the implant was excellent. Future clinical applications are planned.
一种用于骨折和截骨内固定的可吸收栓子，直径4.5毫米，长度30毫米，采用自增强纤维增强基体制造技术由聚-L-丙交酯制成。为提高该装置的旋转稳定性和抓地力，栓子设有可展开的远端鳍片。该栓子用于20只兔子的股骨远端横向截骨固定。对每组五只兔子进行组织学、组织形态计量学和显微放射学研究，观察时间为三周、六周、12周或24周，以研究截骨的愈合情况。15处截骨显示骨愈合。五只兔子的截骨处未形成跨越截骨的小梁，但这些兔子属于随访时间最短的三周或六周组。未遇到栓子的机械故障，植入物的短期生物相容性极佳。计划开展未来的临床应用。
