Koskikare K, Pihlajamäki H, Pätiälä H, Rokkanen P
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Finland.
Ann Chir Gynaecol. 1997;86(3):261-8.
We have developed the intraosseal plating method with self-reinforced poly-L-lactide (SR-PLLA) plates. In the present study for comparison, the other plates were implanted on both sides of the bone because two plates separated by a 2-5 mm bony bridge in the intraosseal fixation proved successful. The two fixation methods may have different effects on the formation of new bone, and we measured this event histomorphometrically.
Osteotomies of the distal femora in 20 adults rabbits were fixed intraosseally with two SR-PLLA plates and four titanium screws and in 20 adult rabbits with identical plates fixed on both sides of the bone with four metallic screws. The follow-up times were three, six, 12, and 24 weeks. The amount of trabecular bone at the osteotomy site was evaluated histomorphometrically.
In both groups and after each follow-up time greater trabecular bone percentage values were noticed on the operated sides. The amount of bone was greatest near the plates and particularly strong between the plates in intraosseal plating.
Intraosseally implanted SR-PLLA plates do not seem to diminish the amount of trabecular bone when compared to similar plates on the bone.
我们已研发出使用自增强聚-L-丙交酯（SR-PLLA）接骨板的骨内固定方法。在本对比研究中，由于骨内固定时两块接骨板被2-5毫米的骨桥隔开已证实成功，所以将其他接骨板植入骨的两侧。这两种固定方法对新骨形成可能有不同影响，我们通过组织形态计量学测量了这一情况。
对20只成年兔的股骨远端进行截骨，用两块SR-PLLA接骨板和四颗钛螺钉进行骨内固定，对另外20只成年兔用同样的接骨板通过四颗金属螺钉固定在骨的两侧。随访时间为3周、6周、12周和24周。通过组织形态计量学评估截骨部位的小梁骨量。
在两组中，每次随访后，手术侧的小梁骨百分比值均更高。骨量在接骨板附近最多，在骨内固定时两块接骨板之间尤其明显。
与骨表面使用类似接骨板相比，骨内植入SR-PLLA接骨板似乎不会减少小梁骨量。
