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[93例甲状腺疾病的促甲状腺激素释放激素试验]

[T.R.H. test in 93 cases of thyroid disease].

作者信息

Murie N, Goasguen J, Almange C, Huguenin A

出版信息

Nouv Presse Med. 1975 Nov 1;4(37):2635-8.

PMID:812062
Abstract

The authors used the stimulation of TSH test by intravenous injection of TRH in 93 patients. They obtained a negative or weak response in thyrotoxicosis, toxic adenomas, and Means syndrome, and a normal response with non-extinctive hot nodules. The response was positive and high in primary hypothyroidism. The results are sometimes paradoxal in hypothalamo-pituitary pathology even after hypophysectomy: a delayed and elevated response is in favour of a pituitary reserve of non-utilised TSH. In non-functional goitres and thyroiditis, the sometimes positive responses obtained are an indication for substitutive and depressive therapy.

摘要

作者对93例患者采用静脉注射促甲状腺激素释放激素(TRH)刺激促甲状腺激素(TSH)试验。他们发现,甲状腺毒症、毒性腺瘤和梅恩斯综合征患者的反应为阴性或弱阳性,非消退性热结节患者反应正常。原发性甲状腺功能减退患者的反应为阳性且反应强烈。即使在垂体切除术后,下丘脑 - 垂体病变患者的结果有时也会自相矛盾:反应延迟且增强提示垂体存在未利用的TSH储备。在非功能性甲状腺肿和甲状腺炎患者中,有时获得的阳性反应是替代和抑制治疗的指征。

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