Reiger J, Quellhorst E, Lowitz H D, Kong R G, Scheler F
Proc Eur Dial Transplant Assoc. 1975;11:158-64.
An ultrafiltration system for the purification of toxic substances is demonstrated. Using this system, it is possible to eliminate substances with a molecular weight up to 5,000 in the same amount as smaller molecules. The clearances for smaller molecules are lower and for larger molecules higher compared to haemodialysis and they depend mainly on the ultrafiltrate flow. Amino acid loss did not exceed the amount which was eliminated by plate haemodialysers. Side effects, such as excessive haemolysis, platelet or fibrinogen depletion, were not to be found.
展示了一种用于净化有毒物质的超滤系统。使用该系统，可以与较小分子以相同的量去除分子量高达5000的物质。与血液透析相比，较小分子的清除率较低，而较大分子的清除率较高，并且它们主要取决于超滤流量。氨基酸损失不超过平板血液透析器所消除的量。未发现诸如过度溶血、血小板或纤维蛋白原消耗等副作用。
