Madjar H, Vetter M, Prömpeler H, Breckwoldt M, Pfleiderer A
Department of Obstetrics and Gynecology, Albert Ludwigs University, Freiburg, Germany.
J Reprod Med. 1993 Dec;38(12):935-40.
Breast vascularization was measured with an 8-MHz continuous wave Doppler pencil probe. Flow values were low in asymptomatic women and high in patients with severe pain or dysplastic changes. Mild treatment with a plant extract produced only a small decrease in breast vascularization. Treatment with norethisterone acetate showed a dose-dependent decrease in blood flow. A good response was seen with a dosage of 5 mg/d, and a dramatic decrease was seen when 10 mg/d was taken. These results showed a good correlation with the patients' symptoms.
使用8兆赫连续波多普勒笔式探头测量乳房血管生成情况。无症状女性的血流值较低，而重度疼痛或发育异常改变的患者血流值较高。用植物提取物进行轻度治疗仅使乳房血管生成有小幅减少。用醋酸炔诺酮治疗显示血流量呈剂量依赖性减少。服用5毫克/天的剂量时效果良好，服用10毫克/天时血流量显著减少。这些结果与患者的症状具有良好的相关性。
