用于检测BrdU标记染色体中姐妹染色单体交换的新染色方法。
New staining method for the detection of sister-chromatid exchanges in BrdU-labelled chromosomes.
作者信息
Alves P, Jonasson J
出版信息
J Cell Sci. 1978 Aug;32:185-95. doi: 10.1242/jcs.32.1.185.
PMID:81211
Abstract
A direct Giemsa technique is described for the selective staining of Brd-U-substituted chromatin. It can advantageously be used for sister-chromatid exchange analysis and for the detailed cytological study of the mouse kinetochores. Presumptive inversions within the centromeric region of chromosomes 4 and 18 in the C57Black/6J mouse are described.
摘要
本文描述了一种用于选择性染色Brd-U取代染色质的直接吉姆萨技术。它可有效地用于姐妹染色单体交换分析以及对小鼠着丝粒进行详细的细胞学研究。文中还描述了C57Black/6J小鼠4号和18号染色体着丝粒区域内可能存在的倒位情况。
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