Castellano M A, Rivero F L, Rodriguez M
Facultad de Psicología, Universidad de La Laguna, Canary Islands, Spain.
Neurosci Lett. 1993 Nov 12;162(1-2):1-4. doi: 10.1016/0304-3940(93)90545-v.
The regulatory action of the contralateral brain side on nigrostriatal dopaminergic (NSDA) neurons was examined in anesthetized rats using extracellular single-unit recording techniques. The spontaneous activity of NSDA cells was recorded from split-brain, sham-lesioned or intact-brain rats. The three groups of cells did not differ in antidromic latency and firing rate. However, cells from split-brain rats exhibited a more regular pattern of discharge than those recorded in the two control groups as shown by autocorrelograms and the standard deviation and variation coefficient of the interspike intervals. In addition, burst firing was found to be markedly reduced in the split-brain group. It is concluded that decussating pathways are involved in the regulation of the discharge pattern of NSDA neurons.
采用细胞外单单位记录技术，在麻醉大鼠中研究了对侧脑半球对黑质纹状体多巴胺能（NSDA）神经元的调节作用。从裂脑、假损伤或完整脑大鼠中记录NSDA细胞的自发活动。三组细胞的逆向潜伏期和放电频率没有差异。然而，如自相关图以及峰峰间期的标准差和变异系数所示，裂脑大鼠的细胞放电模式比两个对照组记录的细胞更规则。此外，发现裂脑组的爆发性放电明显减少。得出的结论是，交叉通路参与了NSDA神经元放电模式的调节。
