Adler L A, Peselow E, Duncan E, Rosenthal M, Angrist B
Psychiatry Service, New York Department of Veterans Affairs Medical Center (DVAMC), NY 10010.
Psychopharmacol Bull. 1993;29(3):371-4.
Alpha-tocopherol (vitamin E) has been found to be effective in the treatment of tardive dyskinesia (TD). Studies to date have been short in duration and have not found long-term carryover effects of vitamin E. The present study examined the persistence of the effects of vitamin E after longer term (36-week) treatment was discontinued. Vitamin E significantly improved TD over this period. However, the effects of vitamin E persisted so that TD scores approached baseline only after 12 weeks of placebo substitution.