Larson E, Anderson J K, Baxendale L, Bobo L
Georgetown University School of Nursing, Washington, DC 20007.
Am J Infect Control. 1993 Dec;21(6):297-301. doi: 10.1016/0196-6553(93)90386-i.
To test the effects of a skin protectant on surgical scrub and glove integrity.
Forty-nine healthy adult volunteers were assigned (12 subjects per group) to apply a protective foam (DermaMed; Benchmark Enterprises, Salt Lake City, Utah) in conjunction with surgical scrub in one of the following formulations: 70% isopropyl alcohol, a liquid detergent base containing 4% chlorhexidine gluconate, a liquid detergent base containing 7.5% povidone-iodine, or a nonantimicrobial liquid soap (control). According to a standard protocol, subjects performed a surgical scrub on 3 days (every other day). Foam was applied after surgical scrub on day 1 and before surgical scrub on day 3. No foam was applied on day 2. Subjects were gloved for 2 hours after surgical scrub.
Laboratory setting.
On all test days, there were significant differences in bacterial reduction by products (chlorhexidine gluconate or alcohol > povidone-iodine > control). When controlling for baseline counts and products used, there were no significant differences in colony-forming unit counts on hands with or without foam immediately after scrubbing or at 2 hours after scrub on gloved or ungloved hands, nor were there differences in glove leakage rates when foam was on hands.
Such protectants can be used without detrimental effects to scrub effectiveness or glove integrity.
测试一种皮肤保护剂对手术刷洗和手套完整性的影响。
49名健康成年志愿者被分配（每组12名受试者），在以下配方之一的手术刷手中使用一种保护性泡沫（DermaMed；Benchmark Enterprises，盐湖城，犹他州）：70%异丙醇、含4%葡萄糖酸氯己定的液体洗涤剂基质、含7.5%聚维酮碘的液体洗涤剂基质或非抗菌液体肥皂（对照）。根据标准方案，受试者在3天内（每隔一天）进行一次手术刷洗。在第1天手术刷洗后和第3天手术刷洗前涂抹泡沫。第2天不涂抹泡沫。受试者在手术刷洗后戴手套2小时。
实验室环境。
在所有测试日，不同产品的细菌减少量存在显著差异（葡萄糖酸氯己定或酒精>聚维酮碘>对照）。在控制基线计数和所使用的产品后，刷洗后立即或戴手套或未戴手套的手在刷洗后2小时，手上有无泡沫时的菌落形成单位计数没有显著差异，手上有泡沫时手套渗漏率也没有差异。
此类保护剂的使用不会对刷洗效果或手套完整性产生不利影响。
