Fontaine G, Umemura J, Di Donna P, Tsezana R, Cannat J J, Frank R
Service de Rythmologie et de Stimulation Cardiqque, Hôpital Jean-Rostand, Ivry-sur-Seine.
Ann Cardiol Angeiol (Paris). 1993 Oct;42(8):399-405.
Arrhythmogenic right ventricular dysplasia (ARVD) may result in sudden death of young and sometimes athletic individuals, while if properly treated it is associated with a good prognosis. It is probably more widespread than currently thought. Comparison of the electrocardiograms of 43 ARVD patients with those of 44 normal individuals provided a new criterion enabling identification of the disease. Measurement of a QRS interval longer than 110 ms in sinus rhythm in lead V1 in an individual with an apparently normal heart enabled identification of the disease with a sensitivity of 55 p. cent and specificity of 100 p. cent if used alone, and a sensitivity of 60 p. cent if used in combination with a prolongation of QRS in lead V3 to greater than 110 ms, but with a specificity of 82 p. cent. After elimination of appearances of right bundle branch block, sensitivity was 50 p. cent for V1. This parameter studied in a hospital population should be validated in minor forms before leading to compulsory ECGs for individuals in high-risk occupations (athletes, public vehicle drivers, etc.).
致心律失常性右室心肌病（ARVD）可能导致年轻个体甚至有时是运动员猝死，而若得到恰当治疗，其预后良好。该病的实际发病率可能比目前认为的更高。对43例ARVD患者和44例正常个体的心电图进行比较，得出了一项能够识别该疾病的新指标。对于心脏看似正常的个体，测量其窦性心律时V1导联QRS间期大于110毫秒，单独使用该指标时识别该病的敏感度为55%，特异度为100%；若与V3导联QRS间期延长至大于110毫秒联合使用，敏感度为60%，但特异度为82%。消除右束支传导阻滞表现后，V1导联的敏感度为50%。在医院人群中研究的这一参数，在用于要求高危职业（运动员、公共交通工具司机等）个体进行强制心电图检查之前，应先在轻症患者中进行验证。
