Alekseevskikh Iu G, Bobkova V P, Razdol'kina T I, Gozalishvili T V, Sergeeva T V
Arkh Patol. 1993;55(6):33-6.
The level of plasma fibronectin (FN) is increasing in prognostically unfavourable morphological forms of childrens glomerulonephritis being in direct relationship with the activity index and sclerosis index. Urine FN excretion depends upon generalization of the tubulointerstitial changes, presence in the kidney of synechia and segmentary sclerosis of the glomeruli capillaries. A direct correlation is established between FN in the renal tissue and the degree of the mesangial cell proliferation and the spread of sclerotic changes.
在儿童肾小球肾炎预后不良的形态学类型中,血浆纤连蛋白(FN)水平升高,且与活动指数和硬化指数直接相关。尿FN排泄取决于肾小管间质改变的广泛性、肾内粘连的存在以及肾小球毛细血管节段性硬化。肾组织中的FN与系膜细胞增殖程度和硬化改变的范围之间存在直接相关性。