Yoshinaga H, Kobayashi K, Sato M, Mizukawa M, Ohtahara S
Department of Child Neurology, Okayama University Medical School, Japan.
Brain Topogr. 1993 Winter;6(2):131-5. doi: 10.1007/BF01191078.
As part of our studies on localization of epileptic foci, dipole analysis using averaged spikes were compared with that using individual spikes for 25 patients with localization related epilepsy. Our results are as follows. 1) In the group which showed stable dipoles from individual spikes, dipole localization from averaged and individual spikes were similar, although the former showed a higher dipolarity and more stable location, for the entire spike discharge including the peak, trough and wave. The high dipolarity was due to improved signal to noise ratio obtained from averaging. 2) The cases with centrotemporal spike focus including benign childhood epilepsy with centrotemporal spikes showed more reliable dipoles. In the cases with frontal lobe epilepsy, reliable dipoles were rarely obtained even with averaged spikes. Each method provided independent information, so they are of complementary value.
作为我们癫痫病灶定位研究的一部分，我们对25例定位相关癫痫患者，比较了使用平均棘波的偶极子分析和使用单个棘波的偶极子分析。我们的结果如下。1）在单个棘波显示偶极子稳定的组中，对于包括峰、谷和波在内的整个棘波放电，平均棘波和单个棘波的偶极子定位相似，尽管前者显示出更高的偶极性和更稳定的位置。高偶极性归因于平均后获得的信噪比提高。2）伴有中央颞区棘波灶的病例，包括伴有中央颞区棘波的良性儿童癫痫，显示出更可靠的偶极子。在额叶癫痫病例中，即使使用平均棘波也很少获得可靠的偶极子。每种方法都提供独立的信息，因此它们具有互补价值。
