Ulrich W D, Ulrich C, Petzel C, Nenning N, Barth T
Abteilung für Funktionsdiagnostik, Neuroophthalmologie und Experimentelle Ophthalmologie, Universitäts-Augenklinik Leipzig.
Ophthalmologe. 1993 Dec;90(6):557-62.
Oculo-pression tonometry (OPT) was introduced in 1984 as a clinical method of examining ocular hydrodynamics. The method involves measuring intraocular pressure (IOP) by applanation tonometry performed before, during and after application of a pressure load that disturbs the dynamic balance between aqueous production and aqueous outflow. From the IOP before (P0) and immediately after (Pr0) the 8-min pressure load period, the outflow facility C(u) can be calculated: [formula: see text] The examinations performed so far have shown that (1) reduced outflow facility can be detected by OPT with a high degree of reliability, and (2) reduced outflow facility is always preceded by the development of glaucoma damage to the optic nerve head. A prospective study has shown that in the group of patients with reduced outflow facility but without glaucoma damage, 73% developed glaucoma damage with typical changes of the papilla and visual field within 3-7 years after the first examination.
眼压迫眼压测量法（OPT）于1984年被引入，作为一种检查眼内流体动力学的临床方法。该方法包括在施加干扰房水生成与房水流出动态平衡的压力负荷之前、期间和之后，通过压平眼压测量法测量眼压（IOP）。根据压力负荷8分钟期间之前（P0）和之后立即（Pr0）的眼压，可以计算出流出率C(u)：[公式：见原文]迄今为止进行的检查表明：（1）OPT能够高度可靠地检测出流出率降低的情况；（2）流出率降低总是先于青光眼对视神经乳头造成损害。一项前瞻性研究表明，在流出率降低但无青光眼损害的患者组中，73%的患者在首次检查后的3至7年内出现了伴有视乳头和视野典型变化的青光眼损害。
