Flipo R M, Castelain V, Sutter B, Danze F, Hardouin P, Duquesnoy B, Delcambre B
Service de Rhumatologie, Centre André Verhaeghe, Hôpital B, CHRU, Lille.
Rev Rhum Ed Fr. 1993 Jun;60(6):463-6.
The frequency of heterotopic ossification in neurological conditions averages 20-25% with variations according to the type of neurological disease and presence or absence of coma. The most common sites are the hips, knees, shoulders, and elbows. Involvement of the hands is an exceedingly rare event of which two instances are reported herein. In both patients evidence of inflammation developed four months after a deep, prolonged coma. Swanneck deformity of the fingers occurred in one case. Juxta-articular ossifications were seen on roentgenograms two months after the onset of symptoms. Both patients had heterotopic ossifications around the shoulders. Erythrocyte sedimentation rate and serum alkaline levels were elevated. Local injections effectively relieved pain in one patient.
神经疾病中异位骨化的发生率平均为20% - 25%,具体发生率因神经疾病类型以及是否存在昏迷而有所不同。最常见的发病部位是髋部、膝部、肩部和肘部。手部受累极为罕见,本文报告了两例。两名患者均在深度、长时间昏迷四个月后出现炎症迹象。其中一例出现手指鹅颈畸形。症状出现两个月后,X线片显示关节周围有骨化。两名患者肩部周围均有异位骨化。红细胞沉降率和血清碱性水平升高。局部注射有效缓解了一名患者的疼痛。