Simonsen L, Stallknecht B, Bülow J
Department of Clinical Physiology/Nuclear Medicine, Bispebjerg Hospital, Copenhagen, Denmark.
Int J Obes Relat Metab Disord. 1993 Dec;17 Suppl 3:S47-51; discussion S68.
Elevated plasma adrenaline is known to increase whole body energy expenditure. We studied the thermogenic effect and the effects on substrate utilization in man during infusion of adrenaline. Two series were performed: in one series skeletal muscle metabolism was investigated and in another series subcutaneous adipose tissue metabolism was investigated. In both series Fick's principle was applied. Intravenous infusion increased blood flow, glucose uptake and oxygen uptake in both skeletal muscle and adipose tissue. It is concluded that skeletal muscle contributes about 40% and adipose tissue about 5% of the whole body adrenaline-induced thermogenesis.
众所周知，血浆肾上腺素水平升高会增加全身能量消耗。我们研究了在输注肾上腺素期间人体的产热效应及其对底物利用的影响。进行了两个系列的实验：一个系列研究骨骼肌代谢，另一个系列研究皮下脂肪组织代谢。在这两个系列中均应用了菲克原理。静脉输注增加了骨骼肌和脂肪组织的血流量、葡萄糖摄取量和氧气摄取量。得出的结论是，骨骼肌对全身肾上腺素诱导的产热贡献约40%，脂肪组织约为5%。
