Tadei A, Geslin P, Delhumeau A, Victor J, Le Douarin L, Richard M
Arch Mal Coeur Vaiss. 1975 Aug;68(8):877-85.
Phentolamine (Regitine) at the dose of 0.3 mg/mn behaves as an arterial and, above all venous, vasodilatator agent, resulting in a marked and early lowering of the pulmonary pressures in acute oedema of the lung and in cardiac asthma. It was used alone in 47 attacks of acute severe left ventricular failure with very favourable results in 43 cases, as proved by the rapid improvement of the haemodynamic status and of the aicd-base balance. Under strict observation, tolerance has been excellent. This therapeutic method seems of great interest in the cases of acute pulmonary oedema with a maintained blood pressure level, and in the forms with severe arterial hypertension which might tolerate larger doses.
酚妥拉明（利其丁）以0.3毫克/分钟的剂量使用时，表现为一种动脉血管扩张剂，尤其是静脉血管扩张剂，可使肺急性水肿和心源性哮喘患者的肺动脉压显著且迅速降低。在47例急性重度左心室衰竭发作中单独使用该药，43例效果非常良好，血液动力学状态和酸碱平衡迅速改善证明了这一点。在严格观察下，耐受性良好。这种治疗方法对于血压维持在一定水平的急性肺水肿病例以及可能耐受更大剂量的重度动脉高血压患者似乎很有意义。
