Modlin I M, Basson M D
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut.
Endocrinol Metab Clin North Am. 1993 Dec;22(4):823-44.
Over 80 peptides and amines secreted by more than 20 different types of neuroendocrine cells scattered throughout the gut have been identified. The physiologic function and clinical relevance of many of these hormones await elucidation. Nevertheless, the clinical use of these agents in either diagnostic or therapeutic modalities has greatly expanded the appreciation of the relevance of many of these peptides to malignant and nonmalignant pathobiology.
现已鉴定出超过20种不同类型散布于整个肠道的神经内分泌细胞所分泌的80多种肽和胺。其中许多激素的生理功能和临床相关性尚待阐明。尽管如此，这些药物在诊断或治疗方式上的临床应用极大地拓展了人们对许多此类肽与恶性和非恶性病理生物学相关性的认识。
