与耐青霉素和头孢菌素的肺炎链球菌菌血症相关的医院内会厌炎
Nosocomial epiglottitis associated with penicillin- and cephalosporin-resistant Streptococcus pneumoniae bacteremia.
作者信息
Daum R S, Nachman J P, Leitch C D, Tenover F C
机构信息
Section of Infectious Diseases, University of Chicago, Illinois.
出版信息
J Clin Microbiol. 1994 Jan;32(1):246-8. doi: 10.1128/jcm.32.1.246-248.1994.
Abstract
We cared for a 4-year-old male with nosocomially acquired epiglottitis caused by Streptococcus pneumoniae. He had been receiving ceftazidime therapy when this infection was recognized. The S. pneumoniae isolate was of serotype 15B and was resistant to beta-lactam antibiotics, cephalosporins (including those with extended spectra), and trimethoprim-sulfamethoxazole. Clinicians and clinical microbiologists must be aware that cephalosporin susceptibility may no longer be assumed for penicillin-resistant S. pneumoniae isolates and that susceptibility testing for the extended-spectrum cephalosporins should be performed whenever this species is isolated from a normally sterile body fluid.
摘要
我们照料了一名4岁男性，他患有由肺炎链球菌引起的医院获得性会厌炎。在确认感染时，他一直在接受头孢他啶治疗。分离出的肺炎链球菌为15B血清型，对β-内酰胺抗生素、头孢菌素（包括那些广谱头孢菌素）和甲氧苄啶-磺胺甲恶唑耐药。临床医生和临床微生物学家必须意识到，对于耐青霉素的肺炎链球菌分离株，不能再假定其对头孢菌素敏感，并且每当从正常无菌的体液中分离出该菌种时，都应进行广谱头孢菌素的药敏试验。
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