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一名孕妇患嗜铬细胞瘤。

Pheochromocytoma in a pregnant patient.

作者信息

Potts J M, Larrimer J

机构信息

Family Practice Residency Program, Metro Health Medical Center, Cleveland, OH.

出版信息

J Fam Pract. 1994 Mar;38(3):289-93.

PMID:8126412
Abstract

Pheochromocytoma accounts for only 0.1% of hypertension found in adults between 40 and 70 years of age. Although it is extremely rare in pregnancy, if it occurs and is unrecognized in pregnant women, pheochromocytoma can have catastrophic effects. For instance, maternal fatal hypertension can be precipitated by anesthesia, vaginal delivery, uterine contractions, or even vigorous fetal movements. Fetal growth retardation is often seen secondary to decreases in uteroplacental perfusion. Fetal hypoxia or death can also occur with maternal episodes of headache, palpitations, and diaphoresis related to tumor secretions. Because many of the signs and symptoms of pheochromocytoma are similar to more frequently encountered hypertensive syndromes related to pregnancy, the diagnosis of pheochromocytoma can be easily overlooked. The case report presented here illustrates the difficulties associated with the diagnosis of pheochromocytoma in a pregnant patient, highlights problems encountered by patients with the tumor, and reviews diagnostic and treatment approaches.

摘要

嗜铬细胞瘤在40至70岁的成年高血压患者中仅占0.1%。虽然其在妊娠期极为罕见,但如果发生在孕妇身上且未被识别,嗜铬细胞瘤可能会产生灾难性后果。例如,麻醉、阴道分娩、子宫收缩甚至剧烈的胎动都可能引发孕产妇致命性高血压。胎儿生长受限常继发于子宫胎盘灌注减少。与肿瘤分泌相关的孕产妇头痛、心悸和出汗发作也可能导致胎儿缺氧或死亡。由于嗜铬细胞瘤的许多体征和症状与更常见的妊娠相关高血压综合征相似,嗜铬细胞瘤的诊断很容易被忽视。本文所呈现的病例报告阐述了妊娠患者诊断嗜铬细胞瘤的困难,突出了肿瘤患者所遇到的问题,并回顾了诊断和治疗方法。

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