Koldewijn E L, Van Kerrebroeck P E, Rosier P F, Wijkstra H, Debruyne F M
Department of Urology, University Hospital Nijmegen, The Netherlands.
J Urol. 1994 Apr;151(4):955-60. doi: 10.1016/s0022-5347(17)35133-9.
To evaluate the effects of central detrusor denervation on bladder compliance, we studied 27 patients with complete suprasacral spinal cord injury in whom intradural posterior sacral root rhizotomies from S2 to S5 in combination with implantation of an intradural Finetech-Brindley bladder stimulator were performed. All patients initially presented with detrusor hyperreflexia. A majority of these patients had a decreased bladder compliance 5 days postoperatively followed by a rapid increase in bladder compliance thereafter. All patients showed persistent detrusor areflexia after long-term followup. In 2 patients incomplete posterior sacral rhizotomies appeared to be performed. These patients had low bladder compliance, so that secondary posterior sacral root rhizotomies at the level of the conus medullaris were done. Intradural rhizotomies of all posterior sacral root components from S2 to S5 in combination with implantation of an anterior sacral root stimulator is a safe and effective procedure in spinal cord injury patients.
为评估中枢性逼尿肌去神经支配对膀胱顺应性的影响,我们研究了27例完全性骶上脊髓损伤患者,这些患者接受了S2至S5硬膜内骶后神经根切断术,并植入了硬膜内Finetech-Brindley膀胱刺激器。所有患者最初均表现为逼尿肌反射亢进。这些患者中的大多数在术后5天膀胱顺应性降低,此后膀胱顺应性迅速增加。长期随访后,所有患者均表现为持续性逼尿肌无反射。有2例患者似乎进行了不完全的骶后神经根切断术。这些患者膀胱顺应性低,因此在脊髓圆锥水平进行了二次骶后神经根切断术。S2至S5所有骶后神经根成分的硬膜内神经根切断术联合骶前神经根刺激器植入术,对于脊髓损伤患者是一种安全有效的手术。