Shinagawa N
First Department of Surgery, Nagoya City University Medical School.
Nihon Rinsho. 1994 Feb;52(2):415-21.
The rate of infection in patients with malignant disease was significantly high than that of patients with benign disease. Enterococcus spp. was the most predominant organism isolated from patients with malignant disease, followed by Staphylococcus spp., Pseudomonas spp., Enterobacter spp. and Klebsiella spp. in order. From patients with benign disease, E. coli was the most predominant organism, followed by Gram negative anaerobes, and Klebsiella spp.. The rate of postoperative infection in the patients with malignant biliary disease was significantly high than that without a risk factor. The rates of bacterial isolation from intraoperative bile culture and wound swab were significantly higher in patient with malignant disease. These findings suggest that the utmost care should be exercised in patients with malignant disease in order to prevent intraoperative contamination with prophylactic antibiotic therapy covering the bacteria isolated from the bile.
恶性疾病患者的感染率显著高于良性疾病患者。肠球菌属是从恶性疾病患者中分离出的最主要微生物，其次依次为葡萄球菌属、假单胞菌属、肠杆菌属和克雷伯菌属。从良性疾病患者中分离出的最主要微生物是大肠杆菌，其次是革兰氏阴性厌氧菌和克雷伯菌属。恶性胆道疾病患者的术后感染率显著高于无危险因素的患者。恶性疾病患者术中胆汁培养和伤口拭子的细菌分离率显著更高。这些发现表明，对于恶性疾病患者应格外小心，以防止术中因预防性使用覆盖从胆汁中分离出的细菌的抗生素治疗而发生污染。
