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一名未经治疗患者的骨髓瘤合并急性髓细胞白血病(作者译)

[Myeloma together with acute myeloblastic leukaemia in an untreated patient (author's transl)].

作者信息

Vallantin X, Tobelem G, Daniel M T, Flandrin G, Brouet J C, Bernard J

出版信息

Nouv Presse Med. 1980 Sep 27;9(35):2559-60.

PMID:6933406
Abstract

In a 66-year old man without previous major disease the unexpected finding of pancytopenia on routine blood count during an acute respiratory infection led to the diagnosis of IgG-producing myeloma without radiological bone lesions, associated with partial blastocytosis and abnormalities in granulocyte maturation. No treatment was given. Within 15 days, the circulating blastocytes became more numerous and type M1 acute myeloblastic leukaemia was diagnosed. A combined rubidazone and cytosine arabinoside treatment failed, and the patient died rapidly.

摘要

在一名无既往重大疾病的66岁男性中,急性呼吸道感染期间常规血常规检查意外发现全血细胞减少,进而诊断为无放射性骨病变的IgG产生型骨髓瘤,伴有部分母细胞增多和粒细胞成熟异常。未给予治疗。15天内,循环中的母细胞数量增多,诊断为M1型急性髓细胞白血病。柔红霉素和阿糖胞苷联合治疗失败,患者很快死亡。

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