Nakano N, Yasumitsu T, Kotake Y, Morino H, Ikezoe J
Department of Surgery, Ehime National Hospital, Japan.
J Thorac Cardiovasc Surg. 1994 Mar;107(3):891-5.
Before operation, we evaluated the usefulness of ultrasonically guided needle biopsy to detect histologically invasion of the chest wall by tumor in patients with lung cancer. Ultrasonically guided needle biopsy, computed tomography, and ultrasonography were done in 29 patients with lung cancer. In all of them, chest wall invasion was histologically confirmed by thoracotomy. As for the diagnosis of chest wall invasion, sensitivity, specificity, and accuracy of ultrasonically guided needle biopsy diagnosis were 61.5%, 100%, and 82.8%, respectively; for diagnosis by computed tomographic scan these figures were 69.2%, 75.0%, and 72.4%, respectively; and for diagnosis by ultrasonography they were 76.9%, 68.8%, and 72.4%, respectively. We had no false-positive cases in the ultrasonically guided needle biopsy assessment and no fatal complications or implantation metastases. Our results indicate that ultrasonically guided needle biopsy is safe and useful for preoperative histologic diagnosis of chest wall invasion in cases in which combined chest wall resection is being considered in patients with lung cancer.
手术前，我们评估了超声引导下针吸活检对检测肺癌患者肿瘤组织学上侵犯胸壁的有效性。对29例肺癌患者进行了超声引导下针吸活检、计算机断层扫描（CT）和超声检查。所有患者均通过开胸手术进行了胸壁侵犯的组织学确认。关于胸壁侵犯的诊断，超声引导下针吸活检诊断的敏感性、特异性和准确性分别为61.5%、100%和82.8%；CT扫描诊断的相应数据分别为69.2%、75.0%和72.4%；超声诊断的相应数据分别为76.9%、68.8%和72.4%。在超声引导下针吸活检评估中我们没有假阳性病例，也没有致命并发症或种植转移。我们的结果表明，对于考虑行胸壁联合切除术的肺癌患者，超声引导下针吸活检对术前胸壁侵犯的组织学诊断是安全且有用的。
