Heidrich R, Markwardt F, Endler S, Hindersin P
J Neurol. 1978 Sep 12;219(1):83-5. doi: 10.1007/BF00313371.
In patients suffering from subarachnoid hemorrhage (SAH), intrathecal administration of p-aminomethylbenzoic acid (PAMBA) was found to produce hemostatically effective concentrations of the antifibrinolytic agent in the cerebrospinal fluid (CSF). The early clinical findings speak in favor of this mode of administration.
在患有蛛网膜下腔出血(SAH)的患者中,发现鞘内注射对氨甲基苯甲酸(PAMBA)可在脑脊液(CSF)中产生具有止血效果的抗纤溶药物浓度。早期临床结果支持这种给药方式。