Hindersin P, Heidrich R
Psychiatr Neurol Med Psychol (Leipz). 1977 Mar;29(3):129-44.
Pathogenetic, diagnostic, and therapeutic problems and questions associated with ruptured cerebral aneurysms assume good knowledge of hemostatic processes. The three factors affecting hemostasia, namely, vasoactive, coagulative, and fibrinolytic risk factors in the blood, cerebro--spinal fluid, and at the site of damage to the vessel wall, are discussed withparticular reference to a thrombosing aneurysm. In the case of secondary hemorrhages it is necessary to determine the cause or pathogenesis, respectively, of the disturbance of coagulation or increase in fibrinolysis in order to be able to take suitable therapeutic measures and reduce the risk of secondary bleeding occurring within the first critical weeks after aneurysmal rupture.
与破裂性脑动脉瘤相关的发病机制、诊断和治疗问题，需要对止血过程有充分的了解。本文将特别结合血栓形成性动脉瘤，讨论影响止血的三个因素，即血液、脑脊液及血管壁损伤部位的血管活性、凝血和纤维蛋白溶解风险因素。对于继发性出血，有必要分别确定凝血障碍或纤维蛋白溶解增加的原因或发病机制，以便能够采取适当的治疗措施，并降低动脉瘤破裂后最初关键几周内发生继发性出血的风险。
