Gath I
J Neurol. 1978 Oct 25;219(2):127-32. doi: 10.1007/BF00314395.
The problem of making a decision in case of two clinical hypotheses is treated by the application of the Neyman-Pearson criterion. As an example, a pneumoencephalographic index (frontal horn width divided by septum-caudate distance) of two different diseases, Huntington's chorea and Parkinsonism, is analyzed. As the aim of the investigator is to detect the maximum number of cases of Huntington's chorea, an appropriately high alpha, (the probability of "false alarm") should be chosen, and maximization of 1-beta (the probability of detection of Huntington's chorea) carried out.
在存在两种临床假设的情况下做出决策的问题，通过应用奈曼 - 皮尔逊准则来处理。例如，分析了两种不同疾病（亨廷顿舞蹈症和帕金森症）的气脑造影指数（额角宽度除以中隔 - 尾状核距离）。由于研究者的目的是检测出最大数量的亨廷顿舞蹈症病例，所以应选择一个适当高的α（“误报”概率），并使1 - β（检测出亨廷顿舞蹈症的概率）最大化。
