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发育中大脑的神经可塑性与儿童皮质视觉障碍

Neuroplasticity of the developing brain and child cortical visual impairment.

作者信息

Pallagrosi M

机构信息

Istituto di Neuropsichiatria Infantile, Università degli Studi La Sapienza, Rome, Italy.

出版信息

Ann Ist Super Sanita. 1993;29(1):163-5.

PMID:8129263
Abstract

Unlike lesions occurring in more steady-state conditions of the adult nervous system, lesions during early phases have additional effects in redirecting subsequent development. It is arguable that this implies enhanced opportunities to mitigate the deleterious effects of such lesions. Further delineation of plasticity and the application of the resulting insights promise therapeutically important advances. Considering the problem of the cortical visual impaired children in a neurodevelopmental key, we illustrate the necessity that we have as clinicians to diagnose as early as possible any case of cortical visual damage in order to foster continued development of the visual nervous system during the period of its greatest flexibility and give the children the maximum opportunity to achieve their still limited visual potential.

摘要

与发生在成人神经系统更稳定状态下的损伤不同,早期阶段的损伤在重新引导后续发育方面具有额外的影响。可以说,这意味着有更多机会减轻此类损伤的有害影响。对可塑性的进一步描述以及由此产生的见解的应用有望在治疗上取得重要进展。从神经发育的关键角度考虑皮质视觉受损儿童的问题,我们说明了作为临床医生尽早诊断任何皮质视觉损伤病例的必要性,以便在视觉神经系统最具灵活性的时期促进其持续发育,并给予儿童最大机会来实现其仍然有限的视觉潜能。

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