用阿芬太尼预处理可减轻丙泊酚引起的疼痛。
Pretreatment with alfentanil reduces pain caused by propofol.
作者信息
Fletcher J E, Seavell C R, Bowen D J
机构信息
Department of Anaesthetics, Royal Hampshire County Hospital, Winchester.
出版信息
Br J Anaesth. 1994 Mar;72(3):342-4. doi: 10.1093/bja/72.3.342.
We have compared two groups (n = 22) of unpremedicated patients to determine if the pain caused by injection of propofol could be modified by alfentanil. In group I, alfentanil 1 mg was given as a bolus i.v. injection 15 s before administration of propofol i.v., while group II received saline. Propofol was given in 20-mg increments every 4 s. All injections were given through the same i.v. cannula on the dorsum of one hand. We found that alfentanil pretreatment reduced pain on injection of propofol (P = 0.001).
我们比较了两组（每组n = 22）未使用术前药的患者，以确定阿芬太尼是否能减轻丙泊酚注射引起的疼痛。第一组在静脉注射丙泊酚前15秒静脉推注1毫克阿芬太尼，而第二组接受生理盐水。丙泊酚以每4秒增加20毫克的速度给药。所有注射均通过同一只手背的静脉留置针进行。我们发现，阿芬太尼预处理减轻了丙泊酚注射时的疼痛（P = 0.001）。
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