Codd M B, Laird O M, Dowling M, Dervan P A, Gorey T F, Stack J P, O'Herlihy B, Ennis J T
Mater Hospital, Dublin, Eire.
Eur J Cancer Prev. 1994 Jan;3 Suppl 1:21-8. doi: 10.1097/00008469-199401001-00004.
The Eccles Breast Screening Programme is a population-based screening programme for breast cancer, based at the Mater Misericordiae Hospital, Dublin. It began in 1989 simultaneously with similar programmes in Belgium, France, Greece, Portugal and Spain. The objectives of the Eccles Programme are: (i) to evaluate the impact of mammographic screening on morbidity and mortality from breast cancer in Irish women; and (ii) to address the feasibility and potential value of a national breast cancer screening programme. The specific group targeted for screening is women born in 1925 to 1940 inclusive, in a defined geographical area comprising north Dublin City and County, and Counties Cavan and Monaghan. The areas combined comprise 16% of the country's population; just over 29,000 women were invited for screening. An analysis of the demographic and socioeconomic features of the target population reveals that it represents the total population remarkably well. Participants were invited from a population register to attend one of two screening units. Follow-up treatment for those with abnormalities takes place predominantly at the Mater Hospital where the facilities of the Departments of Pathology, Surgery and Oncology have been made available to the programme. Almost 18,000 women had a mammogram in the first round of screening, an overall response rate of 62%. A total of 129 cancers were detected, a prevalence of breast cancer of 7.2 per 1,000. Of those, 15 (11.6%) were entirely intraduct, and an additional 7 (5.4%) had minimal invasion. This is considerably higher than the proportion of intraduct cancers seen in referral practice populations.
埃克尔斯乳腺筛查项目是一项基于人群的乳腺癌筛查项目，位于都柏林的仁慈圣母医院。该项目于1989年启动，与比利时、法国、希腊、葡萄牙和西班牙的类似项目同时开展。埃克尔斯项目的目标是：（i）评估乳腺钼靶筛查对爱尔兰女性乳腺癌发病率和死亡率的影响；（ii）探讨全国乳腺癌筛查项目的可行性和潜在价值。筛查的特定目标群体是1925年至1940年（含）出生的女性，涵盖都柏林市北部和郡、卡万郡和莫纳汉郡这一特定地理区域。这些地区的人口总和占该国人口的16%；超过29,000名女性被邀请参加筛查。对目标人群的人口统计学和社会经济特征分析表明，它能很好地代表总人口。参与者从人口登记册中被邀请到两个筛查单位之一参加筛查。对异常者的后续治疗主要在圣母医院进行，病理学、外科和肿瘤学部门的设施已提供给该项目使用。在第一轮筛查中，近18,000名女性进行了乳房X光检查，总体响应率为62%。共检测出129例癌症，乳腺癌患病率为每1000人中有7.2例。其中，15例（11.6%）完全为导管内癌，另有7例（5.4%）有微小浸润。这一比例远高于转诊实践人群中导管内癌的比例。
