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[冠状动脉扩张剂对缺血期间冠状动脉阻力增加的影响]

[Effect of coronary vasodilator agents on the increase of coronary resistance during ischemia].

作者信息

Schäfer W, Böttcher H

出版信息

Langenbecks Arch Chir. 1975;Suppl:65-9.

PMID:813073
Abstract

Following normothermic cardiac arrest an increase of the coronary resistance and a decrease of the cross section of the coronary arteries have been measured as a function of the duration of the ischaemic period during intermittent coronary perfusion. A significant decrease of the coronary resistance, however, was observed when nitroglycerin or papaverin were perfused during the ischaemic period. This therapeutic procedure may improve myocardial circulation, which is insufficient during the post-ischaemic phase, and provides a better basis for a successful resuscitation of the heart.

摘要

在常温心脏骤停后,在间歇性冠状动脉灌注期间,已测量到冠状动脉阻力增加以及冠状动脉横截面积减小,这是缺血期持续时间的函数。然而,当在缺血期灌注硝酸甘油或罂粟碱时,观察到冠状动脉阻力显著降低。这种治疗方法可能会改善缺血后阶段不足的心肌循环,并为心脏成功复苏提供更好的基础。

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