铅与人类红细胞相互作用的动力学
Kinetics of lead interaction with human erythrocytes.
作者信息
Barltrop D, Smith A M
出版信息
Postgrad Med J. 1975 Nov;51(601):770-3. doi: 10.1136/pgmj.51.601.770.
Abstract
The kinetics of the interaction of lead with human erythrocytes has been investigated by means of tracer studies with Pb. The elution characteristics of lead from erythrocytes in contact with EDTA suggest the existence of two binding sites differing in their affinity for lead. The findings are consistent with the existence of two compartments for lead binding in the cell, and a model system based on this concept is proposed.
摘要
通过铅的示踪研究，对铅与人体红细胞相互作用的动力学进行了研究。与乙二胺四乙酸（EDTA）接触的红细胞中铅的洗脱特性表明，存在两个对铅亲和力不同的结合位点。这些发现与细胞中铅结合的两个区室的存在相一致，并基于这一概念提出了一个模型系统。
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