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[刺激家兔下丘脑不同区域时视皮层神经元自发活动和诱发性活动的变化]

[A change in the spontaneous and evoked activity of rabbit visual cortex neurons upon stimulation of different regions of the hypothalamus].

作者信息

Kozhechkin S N, Zhadina S D, Bondar' G G, Nesterova I V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1975 Nov-Dec;25(6):1274-83.

PMID:813416
Abstract

The influence of stimulation of different hypothalamic areas on spontaneous and flash evoked electrical activity of visual cortex neurones was studied in acute experiments on rabbits by means of extracellular records. Stimulation of most parts of the hypothalamus depressed both kinds of neural activity. Stimulation of the ventro-caudal part of the lateral hypothalamic area and the supramammillar area alone resulted in a pronounced facilitation of the cortical unit activity. Localization of the facilitating areas coincides with the zones of maximum positive reinforcement in selfstimulation. The data are discussed in relation to the mechanisms of motivational behaviour.

摘要

通过细胞外记录法,在对家兔进行的急性实验中研究了刺激下丘脑不同区域对视觉皮层神经元自发和闪光诱发电活动的影响。刺激下丘脑的大部分区域会抑制这两种神经活动。仅刺激下丘脑外侧区腹尾部分和乳头体上区会导致皮层单位活动明显增强。促进区域的定位与自我刺激中最大正强化区域相吻合。结合动机行为的机制对这些数据进行了讨论。

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