Prince M R
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston.
Radiology. 1994 Apr;191(1):155-64. doi: 10.1148/radiology.191.1.8134563.
To evaluate the potential for preferential arterial enhancement at magnetic resonance (MR) aortography with an intravenous infusion of paramagnetic contrast material.
Gadolinium chelates were administered intravenously (0.2 mmol/kg) during three-dimensional MR imaging (1.5 T) in 125 patients (77 male and 48 female patients, aged 4-86 years [mean, 66 years]) with suspected aorta or aortic branch vessel disease.
Infusion for the duration of the MR acquisition resulted in significant preferential arterial enhancement without the confounding effects of excessive venous or background-tissue enhancement (P < 10(-5)). Angiographic or surgical correlation in 48 patients revealed an 88% sensitivity and a 97% specificity for detection of stenoses or occlusions and a 100% sensitivity and a 100% specificity for detection of aortic or iliac artery aneurysms.
Preferential arterial enhancement is possible at MR aortography with an intravenous infusion of paramagnetic contrast material.
评估静脉输注顺磁性对比剂时磁共振(MR)主动脉造影实现动脉优先强化的可能性。
在125例(77例男性和48例女性,年龄4 - 86岁[平均66岁])疑似主动脉或主动脉分支血管疾病的患者中,于三维MR成像(1.5T)期间静脉注射钆螯合物(0.2 mmol/kg)。
在MR采集期间进行输注可实现显著的动脉优先强化,且无过多静脉或背景组织强化的混杂影响(P < 10⁻⁵)。48例患者的血管造影或手术相关性显示,检测狭窄或闭塞的敏感性为88%,特异性为97%;检测主动脉或髂动脉瘤的敏感性和特异性均为100%。
静脉输注顺磁性对比剂时,MR主动脉造影可实现动脉优先强化。