筛查发现及有症状的导管原位癌：乳腺钼靶特征与病理对照

Screening-detected and symptomatic ductal carcinoma in situ: mammographic features with pathologic correlation.

作者信息

Evans A J, Pinder S, Ellis I O, Sibbering M, Elston C W, Poller D N, Wilson R

机构信息

Department of Radiology, Nottingham City Hospital, England.

出版信息

Radiology. 1994 Apr;191(1):237-40. doi: 10.1148/radiology.191.1.8134579.

DOI:10.1148/radiology.191.1.8134579

PMID:8134579

Abstract

PURPOSE

To compare the mammographic and pathologic features of screening-detected and symptomatic ductal carcinoma in situ (DCIS).

MATERIALS AND METHODS

The mammographic and pathologic features of 54 screening-detected and 77 symptomatic cases of DCIS were compared. Patients were aged 30-76 years (mean, 58 years).

RESULTS

Diffuse involvement was seen in 10 patients (13%) with symptoms but in none of the screening-detected group (P < .05). The disease was radiologically more extensive in the symptomatic group. Calcifications in the symptomatic group (n = 48) were less likely to have a ductal distribution than those in the screening-detected group (n = 48) (30 [63%] vs 40 [83%], respectively; P < .05). At histologic examination in some cases, the symptomatic group (n = 76) included eight (11%) patients with cribriform-micropapillary, large-cell tumors (P < .05) and less comedocarcinoma (20 [26%] vs 23 [45%], respectively; P < .05) compared with the screening-detected group (n = 51).

CONCLUSION

The results show differences in the radiologic and pathologic features of screening-detected and symptomatic DCIS.

摘要

目的

比较筛查发现的和有症状的导管原位癌（DCIS）的乳腺X线特征和病理特征。

材料与方法

比较了54例筛查发现的和77例有症状的DCIS病例的乳腺X线特征和病理特征。患者年龄在30 - 76岁之间（平均58岁）。

结果

10例（13%）有症状的患者出现弥漫性累及，但筛查发现组无一例出现（P <.05）。有症状组的疾病在放射学上范围更广。有症状组（n = 48）的钙化灶呈导管分布的可能性低于筛查发现组（n = 48）（分别为30例[63%]对40例[83%]；P <.05）。在某些病例的组织学检查中，与筛查发现组（n = 51）相比，有症状组（n = 76）包括8例（11%）筛状微乳头型、大细胞型肿瘤患者（P <.05），粉刺癌较少（分别为20例[26%]对23例[45%]；P <.05）。