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加勒比地区A&B型杆菌肽对嗜皮菌病病例疗效的研究

Study of efficacy of Lamstreptocide A & B on cases of dermatophilosis within the Caribbean.

作者信息

Isitor G N, Njoku C O, Adogwa A O, Oyekan A O

机构信息

School of Veterinary Medicine, Faculty of Medical Sciences, University of The West Indies, St. Augustine, Trinidad, Tobago.

出版信息

Rev Elev Med Vet Pays Trop. 1993;46(1-2):303-8.

PMID:8134646
Abstract

The efficacy of Lamstreptocide A & B was studied on 9 natural cases of bovine and caprine dermatophilosis in 8 different farms in St. Kitts, employing standard histopathologic and bacteriological methods. The lesions of 5 of the treated cases were dried-up, and there was marked peeling-off of scabs of a severely affected case exposing erythematous underlying tissue, at 3 weeks post-application of the product. Apart from 3 mild cases which were not available for follow-up studies and which were reported to have recovered, there was no outright recovery of the 5 animals after treatment at 3 weeks, and even after a second application of the product. An in vitro sensitivity test of the product revealed a slowing down of growth of Dermatophilus congolensis at concentrations in excess of 1% by agar-streak method. However, there was no inhibition of growth of the bacterium by an agar-impregnated sensitivity method.

摘要

采用标准组织病理学和细菌学方法,对圣基茨8个不同农场的9例牛和山羊皮肤嗜皮菌病自然病例进行了A&B链霉素疗效研究。在施用该产品3周后,5例治疗病例的病变干涸,1例严重感染病例的痂皮明显脱落,露出红斑状的皮下组织。除3例轻症病例无法进行后续研究且据报告已康复外,5只动物在3周治疗后及甚至再次施用该产品后均未完全康复。该产品的体外敏感性试验表明,通过琼脂划线法,当浓度超过1%时,刚果嗜皮菌的生长会减缓。然而,用琼脂浸渍敏感性方法时,该细菌的生长未受到抑制。

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Study of efficacy of Lamstreptocide A & B on cases of dermatophilosis within the Caribbean.加勒比地区A&B型杆菌肽对嗜皮菌病病例疗效的研究
Rev Elev Med Vet Pays Trop. 1993;46(1-2):303-8.
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