Fisher B, Klein D L
Am J Gastroenterol. 1975 Nov;64(5):371-5.
An 81-year old man who had a plasmacytoma of the ileum presented with melena for which no bleeding site could be established before surgery. He developed intussusception and the tumor was located at laparotomy. Metastases to the skin and axillary lymph nodes were documented prior to his operation, to mesenteric lymph nodes at surgery and to intrathoracic lymph nodes and a substernal goiter at autopsy. The liver, spleen, bones and marrow were not involved by myeloma or amyloid. Immunoelectrophoresis demonstrated an Ig-A (lambda) monoclonal protein in the serum (with nondiagnostic serum zone electrophoresis patterns) and lambda light chains in the urine. Immunoflourescense of Ig-A (lambda) globulin was present in imprint preparations from the bowel tumor.
一名81岁患有回肠浆细胞瘤的男性出现黑便，术前未能确定出血部位。他发生了肠套叠，剖腹手术时发现了肿瘤。术前记录有皮肤和腋窝淋巴结转移，手术时发现肠系膜淋巴结转移，尸检时发现胸内淋巴结和胸骨后甲状腺肿转移。肝脏、脾脏、骨骼和骨髓未受骨髓瘤或淀粉样变性累及。免疫电泳显示血清中有Ig - A（λ）单克隆蛋白（血清区带电泳图谱无诊断意义），尿中有λ轻链。肠道肿瘤印片标本中存在Ig - A（λ）球蛋白的免疫荧光。
