恶性黑色素瘤的生物化学
Biochemistry of malignant melanoma.
作者信息
Schwartz M K
出版信息
Ann Clin Lab Sci. 1976 Jan-Feb;6(1):56-64.
PMID:813557
Abstract
The biochemistry of malignant melanoma is reviewed. The biosynthesis of melanin from tyrosine is described and the role of tyrosinase and other enzymes in melanoma considered. Detailed methods for the assay of free catechols, their metabolites and urinary indole melanogens are included. Normal values for these constituents and their significance in the evaluation of melanoma patients are discussed.
摘要
本文综述了恶性黑色素瘤的生物化学。描述了从酪氨酸合成黑色素的过程，并探讨了酪氨酸酶和其他酶在黑色素瘤中的作用。文中还包含了测定游离儿茶酚、其代谢产物及尿中吲哚黑素原的详细方法。讨论了这些成分的正常数值及其在评估黑色素瘤患者中的意义。
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