Lur'e L M, Verkhovtseva T P, Levitov M M
Antibiotiki. 1975 Apr;20(4):291-5.
The two-phase pattern of penicillin biosynthesis was observed only under definite cultivation conditions. When the conditions of the culture growth changed, the productivity curve also changed. The most high productivity levels on the glucose medium and the medium with glucose and lactose were noted at the beginning and in the middle of the process respectively. Under more or less equal conditions the productivity remained at the same level.
青霉素生物合成的两相模式仅在特定培养条件下观察到。当培养生长条件发生变化时,生产率曲线也会改变。在葡萄糖培养基以及含有葡萄糖和乳糖的培养基上,最高生产率水平分别出现在过程开始时和过程中间。在大致相同的条件下,生产率保持在同一水平。