Niunikova O I, Potapnev F V, Skuratovich A A, Nikolaeva I V, Danilova T N
Antibiotiki. 1975 Apr;20(4):373-7.
The therapeutic efficiency of kanamycin and vibromycin in treatment of gonorrhea was studied on 112 and 86 males respectively. Clinical and etiological recovery was observed in 85.6 and 92.9 per cent of the patients. The best therapeutic results were obtained with the use of vibromycin in a course dose of 500 mg. A single administration of the drug in a course dose of 300 mg was less effective. The gonococci disappeared from the urethra secretion under the effects of kanamycin and vibromycin 4-10 hours after beginning of the treatment. The minimum concentration of vibromycin inhibiting the gonococcal growth on nutrient media ranged from 0.02 to 0.4 units/ml.
分别对112名和86名男性研究了卡那霉素和强力霉素治疗淋病的疗效。观察到85.6%和92.9%的患者临床和病因学上康复。使用500毫克疗程剂量的强力霉素可获得最佳治疗效果。单次给予300毫克疗程剂量的药物效果较差。在治疗开始后4至10小时,卡那霉素和强力霉素的作用使尿道分泌物中的淋球菌消失。强力霉素在营养培养基上抑制淋球菌生长的最低浓度范围为0.02至0.4单位/毫升。