Mansell M A, Jones N F, Ziroyannis P N, Marson W S
Lancet. 1978 Oct 14;2(8094):803-5. doi: 10.1016/s0140-6736(78)92586-2.
Urinary activity of the enzyme, N-acetyl-beta-D-glucosaminidase (N.A.G.) was examined as a screening test for renal disease in patients with hypertension. Renal disease was present in 64% of patients with increased N.A.G., compared with only 14% of patients with normal N.A.G. The measurement of N.A.G. is cheap and convenient and this simple test warrants further assessment in hypertension as a guide to the need for further investigation.
对高血压患者进行了尿中N-乙酰-β-D-氨基葡萄糖苷酶（N.A.G.）的活性检测，作为肾病的筛查试验。N.A.G.升高的患者中64%存在肾病，而N.A.G.正常的患者中只有14%存在肾病。N.A.G.的检测成本低廉且方便，这项简单的试验值得在高血压患者中进一步评估，以指导是否需要进一步检查。
