Steinmetz J E, Logue S F, Miller D P
Department of Psychology, Indiana University, Bloomington 47405.
Behav Neurosci. 1993 Dec;107(6):941-54. doi: 10.1037//0735-7044.107.6.941.
The development of standard within-subject conditioning tasks for studying similarities and differences in the neural substrates of appetitive and aversive learning is described. Rats learned to press a bar during a brief tone presentation to receive a food pellet reward (the appetitive task). Using the same tone signal, conditioning chamber, and trial timing parameters, the same rats were then trained to press the bar during the tone presentation to avoid a mild footshock (the aversive task). As an initial study of the neural substrates of these forms of learning, the involvement of the cerebellum was assessed. Bilateral lesions of the deep cerebellar nuclei prevented the learning of the aversive task but had no effect on the learning of the appetitive task.
本文描述了用于研究食欲性和厌恶性学习神经基质异同的标准受试者内条件任务的发展情况。大鼠学会在短暂的音调呈现期间按压杠杆以获得食物颗粒奖励（食欲性任务）。使用相同的音调信号、条件反射箱和试验时间参数，然后对相同的大鼠进行训练，使其在音调呈现期间按压杠杆以避免轻微的足部电击（厌恶性任务）。作为对这些学习形式神经基质的初步研究，评估了小脑的参与情况。双侧小脑深部核团损伤阻止了厌恶性任务的学习，但对食欲性任务的学习没有影响。
