Baker R I, Manoharan A, de Luca E, Begley C G
Department of Clinical Haematology, St George Hospital, Sydney, Australia.
Br J Haematol. 1993 Nov;85(3):619-22. doi: 10.1111/j.1365-2141.1993.tb03359.x.
We describe a 31-year-old patient with pure red cell aplasia of pregnancy, successfully managed with regular blood transfusions. In vitro studies showed specific inhibition of day 14 erythroid colonies (BFU-E) using serum and purified immunoglobulin G (IgG) obtained from the patient at diagnosis (before blood transfusion). The inhibition of BFU-E disappeared when haematological remission occurred 3 weeks after delivery and she remains clinically well with a normal haemoglobin 4 years later.
我们描述了一名31岁的妊娠合并纯红细胞再生障碍性贫血患者，通过定期输血成功治疗。体外研究显示，使用诊断时（输血前）从该患者获得的血清和纯化免疫球蛋白G（IgG）对第14天的红系集落（BFU-E）有特异性抑制作用。产后3周血液学缓解时，BFU-E的抑制作用消失，4年后她临床状况良好，血红蛋白正常。
