Schild H H, Weber W, Boeck E, Mildenberger P, Strunk H, Düber C, Grebe P, Schadmand-Fischer S, Thelen M
Klinik mit Poliklinik für Radiologie, Johannes-Gutenberg-Universität Mainz.
Rofo. 1994 Mar;160(3):218-21. doi: 10.1055/s-2008-1032410.
16 DSA investigations using intra-arterial Gd-DTPA were performed on 12 patients. The contrast medium was administered either as a 0.5 molar gadolinium solution (commercially available) or diluted with distilled water to a 0.2-0.4 molar gadolinium solution. The injection was made either by pressure injector or by hand. The aortic arch, abdominal aorta and pelvic and lower limb arteries were examined. 14 of the 16 procedures were diagnostically adequate, but compared with iodinated contrast materials, contrast was less marked. There were no cardiovascular, neurological or allergic side effects. Three patients suffered a feeling of heat and one patient had mild pain during the injection. Even large volumes rapidly injected (up to 20 ml/s of the commercially available solution) were well tolerated. DSA with intra-arterial Gd-DTPA seems to be a suitable alternative for vascular imaging if iodine-containing contrast materials are contraindicated.
对12例患者进行了16次使用动脉内钆喷酸葡胺（Gd-DTPA）的数字减影血管造影（DSA）检查。造影剂要么作为0.5摩尔钆溶液（市售）给药，要么用蒸馏水稀释成0.2 - 0.4摩尔钆溶液。注射通过压力注射器或手动进行。检查了主动脉弓、腹主动脉以及盆腔和下肢动脉。16例检查中有14例诊断充分，但与碘化造影剂相比，造影效果不那么明显。未出现心血管、神经或过敏副作用。3例患者在注射时有发热感，1例患者在注射时出现轻微疼痛。即使快速注射大量造影剂（市售溶液高达20 ml/s）也耐受性良好。如果含碘造影剂禁忌，动脉内注射Gd-DTPA进行DSA似乎是血管成像的合适替代方法。
