Sparenberg A, Hamm B, Hammerer P, Samberger V, Wolf K J
Klinik für Radiologie, Abteilung für Röntgendiagnostik, Universitäts-Klinikum Steglitz, Freie Universität, Berlin.
Rofo. 1991 Aug;155(2):117-22. doi: 10.1055/s-2008-1033231.
85 patients suffering from urinary bladder carcinoma were examined by magnetic resonance imaging in a prospective study. Following precontrast diagnosis, 15 patients were given an intravesicular application of gadolinium-DTPA (Gd-DTPA). Another 35 patients received an intravenous bolus of GD-DTPA. A diagnostic advantage was achieved in only 2 of 15 tumours by using intravesicular contrast application. Compared to the precontrast diagnosis, a 14% improvement from 69% (precontrast) to 83% (contrast medium) was seen with Gd-DTPA applied intravenously in the diagnosis of the tumour stage. The diagnostic gain lies in the improved tumour recognition, the improved demarcation of papillary, non-muscle-infiltrating tumours and in the more definite diagnosis of infiltration into neighbouring organs and the pelvic wall. Demarcation of perivesicular fatty infiltration is rendered more difficult by Gd-DTPA.
在一项前瞻性研究中,对85例膀胱癌患者进行了磁共振成像检查。在造影前诊断后,15例患者膀胱内应用钆喷酸葡胺(Gd-DTPA)。另外35例患者静脉推注Gd-DTPA。膀胱内应用造影剂仅在15个肿瘤中的2个显示出诊断优势。与造影前诊断相比,静脉注射Gd-DTPA诊断肿瘤分期时,诊断准确率从造影前的69%提高到83%,提高了14%。诊断优势在于提高了肿瘤识别能力,改善了乳头状、非肌层浸润性肿瘤的边界划分,以及更明确地诊断对邻近器官和盆腔壁的浸润。Gd-DTPA使膀胱周围脂肪浸润的边界划分更加困难。