Chugh K S, Sharma S C, Singh V, Sakhuja V, Jha V, Gupta K L
Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Dermatology. 1994;188(2):108-12. doi: 10.1159/000247112.
A total of 157 renal allograft recipients were followed for over 1-23 months for the development of dermatological lesions. The non-infective lesions related to immunosuppressive drugs included cushingoid features in 133 (84.7%), xerosis in 120 (76.4%), striae in 69 (43.9%), hypertrichosis in 65 (21.6%), facial erythema in 42 (26.7%) and friable skin in 34 (21.4%) patients. Of the infective lesions, cutaneous mycoses were the most frequent (82.6%) and included tinea corporis and cruris in 82 (52.2%), tinea versicolor in 21 (13.3%), candidiasis in 7 (4%), onychomycosis in 4 (2%) and cryptococcosis in 2 (1.2%) patients. Viral infections included those due to herpes zoster in 17 (10.8%), herpes simplex in 5 (3.1%) and viral warts in 13 (8.2%) patients. Cutaneous malignancy was seen in 1 patient only.
共有157例肾移植受者接受了1至23个月的随访，以观察皮肤病变的发生情况。与免疫抑制药物相关的非感染性病变包括133例（84.7%）出现库欣样特征、120例（76.4%）出现皮肤干燥、69例（43.9%）出现萎缩纹、65例（21.6%）出现多毛症、42例（26.7%）出现面部红斑以及34例（21.4%）出现皮肤脆薄。在感染性病变中，皮肤真菌病最为常见（82.6%），包括82例（52.2%）体股癣、21例（13.3%）花斑癣、7例（4%）念珠菌病、4例（2%）甲癣和2例（1.2%）隐球菌病。病毒感染包括17例（10.8%）带状疱疹、5例（3.1%）单纯疱疹和13例（8.2%）病毒疣。仅1例出现皮肤恶性肿瘤。
