膳食脂肪酸组成对大鼠脂肪组织和肝脏中甘油磷酸酰基转移酶活性的影响。

Effects of dietary fatty acid composition on glycerophosphate acyltransferase activity in rat adipose tissue and liver.

Rule D C

Department of Animal Science, University of Wyoming, Laramie 82071-3684.

Int J Biochem. 1994 Jan;26(1):49-54. doi: 10.1016/0020-711x(94)90194-5.

Abstract

How source of dietary fat influences glycerophosphate acyltransferase (GPAT) activity in homogenates of adipose tissue and liver was determined using 5 rats per diet that contained 12% fat from either corn- (CO), high-oleate-safflower (HOSO), palm- or high-stearate-oils. 2. Activity was greatest in adipose tissue homogenates of rats fed HOSO and CO whereas no treatment effects were observed in liver homogenates. 3. No differences in fat pad weights were observed; thus HOSO- and CO-diets likely depressed other lipid synthetic rates. 4. Data indicate that mono- and diunsaturated fatty acid diets supported greater adipose tissue GPAT activity than did saturated fat diets when fed to rats.

摘要

使用每组5只大鼠，确定膳食脂肪来源如何影响脂肪组织和肝脏匀浆中的甘油磷酸酰基转移酶（GPAT）活性，这些大鼠食用的每种饮食含有12%来自玉米油（CO）、高油酸红花油（HOSO）、棕榈油或高硬脂酸油的脂肪。2. 喂食HOSO和CO的大鼠脂肪组织匀浆中的活性最高，而在肝脏匀浆中未观察到处理效应。3. 未观察到脂肪垫重量的差异；因此，HOSO和CO饮食可能降低了其他脂质合成速率。4. 数据表明，当喂给大鼠时，单不饱和脂肪酸和多不饱和脂肪酸饮食比饱和脂肪饮食更能支持脂肪组织中更高的GPAT活性。