Rajalekshmy K R, Abitha A R, Pramila R, Gnanasagar T, Maitreyan V, Shanta V
Haematology/Immunology Division, Cancer Institute, Adyar, Madras, South India.
Leuk Res. 1994 Mar;18(3):183-90. doi: 10.1016/0145-2126(94)90113-9.
At the Cancer Institute, Madras, India, we have performed immunophenotyping in 125 untreated cases of acute lymphoblastic leukaemia using a panel of 16 monoclonal antibodies and the avidin-biotin immunoperoxidase technique in a haematology autoanalyser (Technicon Hi system). Our results demonstrate a marked difference in the phenotypic pattern of ALL compared to Western countries, the predominant finding being a relative excess of T-ALL and a paucity of C-ALL cases. Age distribution of C-ALL reveals a peak at 2-6 years in paediatric ALL cases.
在印度马德拉斯癌症研究所，我们使用一组16种单克隆抗体以及抗生物素蛋白-生物素免疫过氧化物酶技术，在血液学自动分析仪（Technicon Hi系统）上对125例未经治疗的急性淋巴细胞白血病病例进行了免疫表型分析。我们的结果表明，与西方国家相比，急性淋巴细胞白血病的表型模式存在显著差异，主要发现是T-ALL相对过多，而C-ALL病例较少。C-ALL的年龄分布显示，在儿童急性淋巴细胞白血病病例中，2至6岁出现一个高峰。
