Zanoio L, Albiero A, Divirgilio G
Istituto di Clinica Ostetrica e Ginecologica, Università degli Studi di Verona.
Minerva Ginecol. 1993 Dec;45(12):591-6.
The Authors carried out a retrospective examination of data relating to 241 patients undergoing radical hysterectomy with pelvic lymphadenectomy between 1970 and 1991. The basic aim of the study was to identify and quantify complications correlated to radical hysterectomy using the Wertheim-Meigs method. Surgery was performed in 223 cases due to cervical cancer, in 13 cases due to endometrial cancer, in 3 cases due to vaginal cancer and in 2 due to ovarian cancer with secondary extension to the uterus. Complications were subdivided into intraoperative and postoperative. Intraoperative complications involved the urinary tract in 4.5% and other apparatus (intestinal and nervous lesions, hemorrhage due to vascular damage) in 8.7% of cases. Postoperative complications were classified as follows: 35.2% involving the urinary tract (fistula 20.3% and vesical dysfunction 14.9%) and 8% involving other organs or systems (infections, neuropathy, pelvic lymphocele, pathologies of intestinal canalization, etc.). Lastly, the Authors examined the individual complications of radical hysterectomy, focusing attention in particular on vesicourethral dyskinesia, in the light of the physiopathological mechanisms reported in the literature. The mean rate of complications in the series examined here was substantially comparable to that reported by other Authors.
作者对1970年至1991年间241例行根治性子宫切除术加盆腔淋巴结清扫术患者的数据进行了回顾性研究。该研究的基本目的是使用韦特海姆-梅格斯(Wertheim-Meigs)方法识别并量化与根治性子宫切除术相关的并发症。223例手术因宫颈癌进行,13例因子宫内膜癌进行,3例因阴道癌进行,2例因卵巢癌继发子宫受累进行。并发症分为术中并发症和术后并发症。术中并发症累及泌尿系统的占4.5%,累及其他器官(肠道和神经损伤、血管损伤出血)的占8.7%。术后并发症分类如下:累及泌尿系统的占35.2%(瘘管占20.3%,膀胱功能障碍占14.9%),累及其他器官或系统的占8%(感染、神经病变、盆腔淋巴囊肿、肠道通路病变等)。最后,作者根据文献报道的生理病理机制,研究了根治性子宫切除术的个体并发症,尤其关注膀胱尿道运动障碍。本系列研究中并发症的平均发生率与其他作者报道的基本相当。