The development of airways obstruction in sarcoidosis among smokers and non-smokers.

The prevalence of respiratory function abnormalities was studied in 32 patients with pulmonary sarcoidosis, 16 (50%) of whom were smokers. Airflow obstruction was found at presentation in one non-smoker and developed in four more during the course of follow-up. Similar airflow obstruction was present in six smoking patients and developed in four patients subsequently. Airways obstruction was a common physiological defect even in non-smokers, though smokers had more frequent airflow obstruction and developed a worse defect.