Marty H, Mazzucchelli L
Medizinische Abteilung Bezirksspital Obersimmental, Zweisimmen.
Schweiz Rundsch Med Prax. 1994 Mar 1;83(9):240-5.
Clinical and histopathological features of cutaneous vasculitis are presented by means of 14 case reports. Proof of vasculitis in skin biopsy consecutively demands for a search of a cause and of the extension of the vasculitic process in the sense of a systemic disease. The most frequent form of cutaneous vasculitis is hypersensitivity angiitis, a disease in which always an exogenous (drugs, infections) or an endogenous (malignant neoplasia, connective tissue disease) trigger should be sought if cutaneous vasculitis persists after removal or treatment of the suspected cause. Then, antihistaminic or--particularly in cases with systemic involvement--immunosuppressive drugs (corticosteroids or cyclophosphamide) should be considered.
通过14例病例报告介绍了皮肤血管炎的临床和组织病理学特征。皮肤活检中血管炎的确诊需要寻找病因以及从系统性疾病的角度确定血管炎进程的范围。皮肤血管炎最常见的形式是超敏性血管炎，如果在去除或治疗可疑病因后皮肤血管炎仍持续存在，那么在这种疾病中总是应该寻找外源性（药物、感染）或内源性（恶性肿瘤、结缔组织病）触发因素。然后，应考虑使用抗组胺药，或者——特别是在有全身受累的情况下——使用免疫抑制药物（皮质类固醇或环磷酰胺）。
